產(chǎn)品名稱：human gene knockout HEK293 cell line
產(chǎn)品規(guī)格：10E6cell/管，2管
產(chǎn)品運(yùn)輸條件：干冰
產(chǎn)品儲存條件和期限：液氮，長期保存
產(chǎn)品優(yōu)勢：
? 敲除有保障，無效退單或重新生產(chǎn)；
產(chǎn)品驗(yàn)收說明：
收到細(xì)胞株包裹時，請立即檢查細(xì)胞株冷凍管是否有解凍情形，若有請立即拍照并通知公司。細(xì)胞株收到后請盡快開展實(shí)驗(yàn)，如果想長期保存請轉(zhuǎn)移至液氮中。
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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